A cutting-edge research initiative led by Dr. Leonardo Salmena at the University of Toronto. The project, titled "Exploring microRNA as Targets for Glioblastoma Therapy”, focuses on developing novel therapeutic strategies to address one of the most aggressive and treatment-resistant forms of brain cancer. 

Glioblastoma (GBM) is the most common and lethal brain malignancy in adults, with fewer than 5% of patients surviving five years after diagnosis. Current treatments are largely ineffective, in part due to a population of cells known as glioblastoma stem cells (GSCs), which are believed to drive tumour growth and resistance to therapy. Despite their importance, significant gaps remain in the understanding of GSC biology. 

This work represents an important advancement in the field, offering a promising path toward more effective treatments for this devastating disease. 

"I'm really proud of our team's hard work in moving this project forward. We truly believe it could change how we think about and treat GBM.”, says Dr. Salmena. “We're very thankful to Brain Cancer Canada and the extraordinary contributions of grass roots fundraisers from across Canada that make this grant possible, including: Run for Jayne, Move to Promote GBM, Ride for Don, Julia Coey Memorial, Farands for the Fight.”